| Mayo Clinic Research news and Discovery's Edge |
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| Beyond weight loss: Bariatric surgery may reduce cancer risk |
| Tuesday, May 7, 2024 |
| When you think about obesity, you may not connect it to cancer. However, researchers long have suspected a link between certain cancers and weight. Among those are endometrial, ovarian, colon, liver, pancreatic and postmenopausal breast cancers, which together contribute to 15 to 20% of all cancer deaths in the U.S. Cancer risk increases with obesity More than one-third of adults in the U.S. are considered obese with a body mass index (BMI) of 30 or higher. BMI is the measure… |
| Electrospinning biotherapies of tomorrow |
| Monday, May 6, 2024 |
| The future of healing disease may involve a syringe, a high voltage power supply and polymer solutions coming together to engineer tissue. Mayo Clinic researchers are studying these different elements now using an electrospinner, a device that whips biotherapeutic fibers into a scaffold — or platform — for spinning regenerative biotherapeutics. An electrospinner is almost like a medical spinning wheel or loom. An electrospinner unleashes electrical forces that churn chemical solutions into nano- or microscopic… |
| Ovarian cancer: New treatments and research |
| Sunday, May 5, 2024 |
| Editor's note: May 8 is World Ovarian Cancer Day. Three cancers — ovarian epithelial cancer, fallopian tube cancer and primary peritoneal cancer — are commonly called ovarian cancer. They arise from the same kind of tissue and are treated similarly. "The ovaries and fallopian tubes are so anatomically close to each other that we sometimes can't tell if the cancer is coming from the ovary or the fallopian tube," says S. John Weroha, M.D., Ph.D., a Mayo… |
| Weight-loss surgery before kidney transplantation improves health and eligibility of patients with obesity and renal failure, Mayo Clinic study finds |
| Thursday, May 2, 2024 |
| ROCHESTER, Minn. — Laparoscopic sleeve gastrectomy promotes relatively rapid weight loss, reduces obesity-related health issues and improves eligibility for kidney transplantation for patients with advanced chronic kidney disease and obesity, according to new research from Mayo Clinic. Patients with advanced chronic kidney failure and severe obesity often are not considered for kidney transplantation, but according to a study published in Mayo Clinic Proceedings, sleeve gastrectomy can improve high-risk patients meeting the criteria for transplantation. The… |
| Mayo Clinic researchers' new tool links Alzheimer's disease types to rate of cognitive decline |
| Tuesday, April 30, 2024 |
| Mayo Clinic researchers have developed a new scoring tool that links Alzheimer's disease subtypes with age of onset and the rate of cognitive decline in individuals. |
| AI may help predict risk of Barrett's esophagus and esophageal cancer |
| Friday, April 26, 2024 |
| Editor's note: April is Esophageal Cancer Awareness Month. Esophageal cancer accounts for only about 1% of new cancer cases in the U.S., far lower than rates in other parts of the world. However, survival rates are low because it is often found at a later stage when symptoms such as difficulty swallowing, worsening heartburn, coughing and hoarseness have begun. Having precancerous changes in the cells of the esophagus, a condition called Barrett's esophagus is a risk factor for esophageal cancer. Barrett's… |
| Global consortium to study Pick's disease, rare form of early-onset dementia |
| Wednesday, April 24, 2024 |
| JACKSONVILLE, Fla. — Pick's disease, a neurodegenerative disease of unknown genetic origin, is a rare type of frontotemporal dementia that affects people under the age of 65. The condition causes changes in personality, behavior and sometimes language impairment. In patients with the disease, tau proteins build up and form abnormal clumps called Pick bodies, which restrict nutrients to the brain and cause neurodegeneration. The only way to diagnose the disease is by looking at brain… |
| Mayo Clinic Minute: Treatment and research of glioblastoma |
| Monday, April 22, 2024 |
| Considered the most aggressive type of brain cancer, glioblastoma grows rapidly, destroying healthy tissue. Globally, approximately 300,000 people are diagnosed each year with glioblastoma. Watch: The Mayo Clinic Minute https://youtu.be/DP7p09z_mOY Journalists: Broadcast-quality video (1:05) is in the downloads at the end of this post. Please courtesy: "Mayo Clinic News Network." Read the script. Glioblastoma is a type of cancer affecting glial cells, which connect nerve cells and support brain function. "It tends to be a… |
| More than 90 articles from 25 countries featured in Mayo Clinic Proceedings: Digital Health journal's first year |
| Wednesday, April 10, 2024 |
| Mayo Clinic Proceedings: Digital Health, an open-access companion journal to the widely read and cited Mayo Clinic Proceedings, is marking its first anniversary, having published more than 90 articles on the digital transformation of healthcare internationally. Authors published in Mayo Clinic Proceedings: Digital Health's first year represent 25 countries on five continents, and the content has had more than 125,000 downloads. Mayo Clinic Proceedings: Digital Health focuses on the translation, adaptation and implementation of digital… |
| New heated drug baths provide hope for patients with stomach cancer |
| Thursday, April 4, 2024 |
| Mayo Clinic researchers used a new approach to chemotherapy to more than double the typical survival rate for patients with stomach cancer and peritoneal metastasis, which is cancer that has spread to the lining of the abdominal cavity. |
| Mayo Clinic study finds active workstations may improve cognitive performance |
| Thursday, April 4, 2024 |
| ROCHESTER, Minn. — A recent Mayo Clinic study suggests that active workstations incorporating a walking pad, bike, stepper and/or standing desk are successful strategies for reducing sedentary time and improving mental cognition at work without reducing job performance. Extended sedentary behavior, whether at work or home, increases a person's risk of preventable chronic diseases. "Our findings suggest that it is feasible to blend movement with office work that previously would have been done during long… |
| New study finds triple-negative breast cancer tumors with an increase in immune cells have lower risk of recurrence after surgery |
| Tuesday, April 2, 2024 |
| ROCHESTER, Minn. — A new multicenter, international study suggests that people who have early-stage triple-negative breast cancer (TNBC) and high levels of immune cells within their tumors may have a lower risk of recurrence and better survival rates even when not treated with chemotherapy. The study was published today in the Journal of American Medical Association (JAMA). TNBC is a breast cancer subtype that does not respond to drugs that target the estrogen receptor or… |
| Could CAR-T cell therapy improve kidney transplants? |
| Tuesday, April 2, 2024 |
| Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a revolutionary approach to organ transplantation for patients who are hard to match and susceptible to rejection, Mayo Clinic researchers discovered. Their pioneering research focuses on using CAR-T cells derived from the patient's own immune system to prevent rejection of donated organs. Sensitized patients are those who have high levels of antibodies that cause their immune systems to react negatively to potential donor organs. These… |
| Mayo Clinic, Terasaki Institute launch collaboration for transplant innovation |
| Monday, April 1, 2024 |
| JACKSONVILLE, Fla. — Mayo Clinic and Terasaki Institute for Biomedical Innovation announced today a research collaboration centered on improving organ transplant outcomes. Beginning in April, Mayo Clinic biomedical researchers and Terasaki Institute scientists will work together on two core areas: real-time monitoring of donated organ health from procurement to transplant surgery and developing predictive technologies to determine which transplant recipients have a higher likelihood of rejection. That will be done by creating prognostic signatures and… |
| Study documents safety, improvements from stem cell therapy after spinal cord injury |
| Monday, April 1, 2024 |
| ROCHESTER, Minn. — A Mayo Clinic study shows stem cells derived from patients' own fat are safe and may improve sensation and movement after traumatic spinal cord injuries. The findings from the phase 1 clinical trial appear in Nature Communications. The results of this early research offer insights on the potential of cell therapy for people living with spinal cord injuries and paralysis for whom options to improve function are extremely limited. In the study… |
| Social isolation linked to biological age gap, higher mortality rate |
| Wednesday, March 20, 2024 |
| Mayo Clinic research finds a connection between Social Network Index score and AI-determined biological age ROCHESTER, Minn. — A new study from Mayo Clinic finds that socially isolated people are more likely to show signs of being biologically older than their age and more likely to die from a variety of causes. The research, published in the Journal of the American College of Cardiology: Advances, suggests that social connection plays an important role in overall… |
| Diversity science researcher achieving goal of making difference in people's lives |
| Saturday, February 10, 2024 |
| From the time she was a young woman, Gladys Asiedu, Ph.D., knew she wanted to help people. Her path to achieving that goal began in Ghana. Learn about her journey and the difference she is making as a diversity science researcher. Gladys Asiedu, Ph.D., always knew she wanted to make a difference in people's lives. A steady focus on that altruistic goal would ultimately lead her to Mayo Clinic. As a child in Ghana in… |
| Aspiring innovators aim to transform medicine with the next big idea |
| Friday, February 9, 2024 |
| Residents and students at Mayo Clinic learning the craft of their careers are also adopting a mindset to transform healthcare. Programs at Mayo are helping these enterprising inventors ask the right questions and take the steps to bring their innovative ideas to market. |
| Genetic testing pinpoints cardiovascular risk in patients with aortic disorders |
| Wednesday, February 7, 2024 |
| A new Mayo Clinic systematic review has shed light on genetically inherited aortic disorders in patients, highlighting the importance of early diagnosis and treatment for those with inherited cardiovascular risk. |
| Growing mini-organs to find new treatments for complex disease |
| Wednesday, January 31, 2024 |
| Microscopic view of an intestinal organoid Mayo Clinic investigators are growing three-dimensional human intestines in a dish to track disease and find new cures for complex conditions such as inflammatory bowel disease. These mini organs function like human intestines with the ability to process metabolites that convert food into energy on a cellular level and secrete mucus that protects against bacteria. These 3D mini intestines in a dish, known as "organoids," provide a unique platform… |
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