|NCI News Releases|
|Study finds premature death rates diverge in the United States by race and ethnicity|
Premature death rates declined among Hispanics, blacks, and Asian/Pacific Islanders due mainly to fewer deaths from cancer, heart disease, and HIV. Rising deaths from accidents, drug overdoses, suicide and liver disease increased rates among whites and American Indian/Alaska Natives.
|TCGA study identifies genomic features of cervical cancer|
Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified novel genomic and molecular characteristics of cervical cancer that will aid in subclassification of the disease and may help target therapies that are most appropriate for each patient.
|New Drug Formulary Will Help Expedite Use of Agents in Clinical Trials|
The National Cancer Institute (NCI) today launched a new drug formulary (the “NCI Formulary”) that will enable investigators at NCI-designated Cancer Centers to have quicker access to approved and investigational agents for use in preclinical studies and cancer clinical trials. The NCI Formulary could ultimately translate into speeding the availability of more-effective treatment options to patients with cancer.
|Early-phase trial demonstrates shrinkage in pediatric neural tumors|
In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.
|Cellular Immunotherapy Targets a Common Human Cancer Mutation|
In a study of an immune therapy for colorectal cancer that involved a single patient, researchers identified a method for targeting the cancer-causing protein produced by a mutant form of the KRAS gene.
|No Safe Level of Smoking: Even low-intensity smokers are at increased risk of earlier death|
People who consistently smoked an average of less than one cigarette per day over their lifetimes had a 64 percent higher risk of earlier death than people who never smoked.
|NCI collaborates with Multiple Myeloma Research Foundation|
The National Cancer Institute (NCI) announced a collaboration with the Multiple Myeloma Research Foundation (MMRF) to incorporate MMRF's wealth of genomic and clinical data on the disease into the NCI Genomic Data Commons (GDC), a publicly available database.
|NCI embraces scientific road map to achieve Cancer Moonshot goals|
National Cancer Institute Acting Director Douglas Lowy, M.D., today accepted, with revisions that reflect NCAB’s discussion, the recommendations of a Blue Ribbon Panel (BRP) on 10 approaches most likely to make a decade’s worth of progress against cancer in five years, a key goal of the White House Cancer Moonshot.
|Oxygen can impair cancer immunotherapy in mice|
Researchers have identified a mechanism in mice by which anticancer immune responses are inhibited within the lungs, a common site of metastasis for many cancers.
|Uncovering a new principle in chemotherapy resistance in breast cancer|
A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.